MCBO Core Lecture II

Natascha Kleiter: T-cell
course documents:
Routy BLe Chatelier EDerosa LDuong CPMAlou MT, [...]Zitvogel L: Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors Science. 2018 Jan 5;359(6371):91-97. doi: 10.1126/science.aan3706. Epub 2017 Nov 2.

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The aim of this lecture is to illustrate the development, differentiation and characteristic features of different CD4 helper subsets (Th1, Th2, Th17, iTregs) and CD8 T cells. The different roles during disease such as asthma, immunodeficiency, autoimmunity, or tumor growth will be discussed.

Suggested reading:
Abul K. Abbas, Andrew H. H. Lichtman, Shiv Pillai: Cellular and Molecular Immunology