Clemens Decristoforo

Univ.Doz, Prof. h.c., Mag.pharm.,Dr.rer.nat.
https://orcid.org/0000-0003-0566-4036

Academic career history:
1991             M Pharm
1991-1997    Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck, Austria
1997             Dr.rer. nat. (equ Ph.D.)
1997-1998    Post Doc Marie Curie Fellow at the Nuclear Medicine Research Laboratory, St Bartholomews Hospital, QMW college, London.
2001        Habilitation (venia docendi) for Radiopharmacy
Since 1998    Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck, Austria
2009-2010    Radiopharmaceutical Scientist, Industrial Applications and Chemistry Section,  Division of Physical and Chemical Sciences, IAEA, Vienna, Austria
Since 2010    Radiopharmacist Clinical Department of Nuclear Medicine Innsbruck and Dozent at the Medical University Innsbruck, Austria
Oct. 2014    Honorary Professor Medical University Innsbruck

List of supervised PhD students (Graduation 2013-2019)
Christine Rangger: 2013
Chuangyan Zhai: 2016
Dominik Summer: 2018
Piryia Kaeopookum: 2019
Joachim Pfister: current

Publications:
130 original papers, 12 reviews, 10 letters, 12 book chapters
HI=46, 7140 Citations (google scholar Dec 2019)

Awards/Prices:
Erwin Schrödinger fellowship/1997-98,
Marie Curie Fellowship 1997-1998
Pfeiffer Stipendium OGN 2004
Mallinckrodt Price OGNMB 2012, THP Preis OGNMB 2012+2015
Best non clinical paper EJNMMI 2012

Peer review activities:
Reviewer for more than 20 peer reviewed journals mainly in the area of Nuclear Medicine, Radiopharmaceuticals Sciences, Medicinal Chemistry, Pharmacy. Additionally, reviewer for DFG, FWO, Swiss cancer league, Dutch cancer Soc

Editorial Board Member:
European Journal of Nuclear Medicine and Molecular Imaging (EJNMMI, Springer), EJNMMI Research, EJNNMI Radiopharmacy& Chemistry, Clinical Transl.Imaging

Past research funding (5 most important, PI):
FWF (P30924-B26) Modified Siderophores for “Theranostics” of Aspergillosis 2018
FWF (P25899-B23) Novel radiometal chelators to develop targeted labelled biomolecules for PET 2013
ERA-NET Transcan A novel biomarker for medullary thyroid cancer (GRAN-T-MTC), FWF I 1224-B19 2013
FWF (L676) 68Ga-siderophores for diagnosis of aspergillosis with PET 2009
Radiolabelled Nanoparticles for specific molecular targeting in oncology, ProjectNr. 815844: V0208-Z07-BI, Austrian NANO Initiative 2008

Key international cooperation partners (last 5 years)
Hubertus Haas, Biozentrum, Medical University Innsbruck
Milos Petrik, IMTM, Palacky University, Olomouc, Czech Republic.
Vladimir Tolmachev, Institute of Immunology, Genetic and Pathology, Uppsala University
Peter Laverman, Dept. of Radiology, Radboud University Medical Center, Nijmegen
Jane Sosabowski, Centre for Molecular Oncology, Barts Cancer Institute, London
Björn Wängler, Molecular Imaging and Radiochemistry, Medical Faculty Mannheim of Heidelberg University, Mannheim
Tobias Ross, Radiopharmazeutischen Chemie, Medizinische Hochschule Hannover

Reviewer:
EJNMMI, JNM, Nucl Med Biol, Biocon Chem, Mol Pharm, Eur J Pharm Sci, EJNMMI research, JLCR, JMC, Nuc Med Commun, Bone, Sci Pharm, Mol Imag, DFG, Swiss cancer league, FWO, Dutch cancer Soc

10 highlighted publications:
Dominik Summer, Javad Garousi, Maryam Oroujeni, Bogdan Mitran, Ken G Andersson, Anzhelika Vorobyeva, John Löfblom, Anna Orlova, Vladimir Tolmachev, Clemens Decristoforo: Cyclic versus Noncyclic Chelating Scaffold for 89Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression. Molecular Pharmaceutics 11/2017; 15(1)., DOI:10.1021/acs.molpharmaceut.7b00787

Stefano Fanti, Rachele Bonfiglioli, Clemens Decristoforo: Highlights of the 30th Annual Congress of the EANM, Vienna 2017: “Yes we can – make nuclear medicine great again”. European journal of nuclear medicine and molecular imaging 05/2018; 45(Suppl 2)., DOI:10.1007/s00259-018-4029-9

Dominik Summer, Leo Grossrubatscher, Milos Petrik, Tereza Michalcikova, Zbynek Novy, Christine Rangger, Maximilian Klingler, Elisabeth von Guggenberg, Roland Haubner, Piriya Kaeopookum, Hubertus Haas, Clemens Decristoforo: Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding. Bioconjugate Chemistry 05/2017; 28(6)., DOI:10.1021/acs.bioconjchem.7b00182

Dariusz Pawlak, Christine Rangger, Petra Kolenc-Peitl, Piotr Garnuszek, MichałMaurin, Laura Ihli, Marko Kroselj, Theodosia Maina, Helmut Maecke, Paola Erba, Leopold Kremser, Alicja Hubalewska-Dydejczyk, Renata Mikolajczak, Clemens Decristoforo: From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial. European Journal of Pharmaceutical Sciences 01/2016; 85., DOI:10.1016/j.ejps.2016.01.023

Chuangyan Zhai, Dominik Summer, Christine Rangger, Gerben M Franssen, Peter Laverman, Hubertus Haas, Milos Petrik, Roland Haubner, Clemens Decristoforo: Novel Bifunctional Cyclic Chelator for 89 Zr Labeling–Radiolabeling and Targeting Properties of RGD Conjugates. Molecular Pharmaceutics 05/2015; 12(6)., DOI:10.1021/acs.molpharmaceut.5b00128

Hubertus Haas, Milos Petrik, Clemens Decristoforo: An Iron-Mimicking, Trojan Horse-Entering Fungi—Has the Time Come for Molecular Imaging of Fungal Infections?. PLoS Pathogens 01/2015; 11(1):e1004568., DOI:10.1371/journal.ppat.1004568

Milos Petrik, Hubertus Haas, Georg Dobrozemsky, Cornelia Lass-Flörl, Anna Helbok, Michael Blatzer, Hermann Dietrich, Clemens Decristoforo: Ga-68-Siderophores for PET Imaging of Invasive Pulmonary Aspergillosis: Proof of Principle. Journal of Nuclear Medicine 04/2010; 51(4):639-45., DOI:10.2967/jnumed.109.072462

Elisabeth von Guggenberg, Werner Sallegger, Anna Helbok, Meltem Ocak, Robert King, Stephen J Mather, Clemens Decristoforo: Cyclic Minigastrin Analogues for Gastrin Receptor Scintigraphy with Technetium-99m: Preclinical Evaluation. Journal of Medicinal Chemistry 07/2009; 52(15):4786-93., DOI:10.1021/jm900400w

Michael Gabriel, Clemens Decristoforo, Dorota Kendler, Georg Dobrozemsky, Dirk Heute, Christian Uprimny, Peter Kovacs, Elisabeth Von Guggenberg, Reto Bale, Irene J Virgolini: 68Ga-DOTA-Tyr3-Octreotide PET in Neuroendocrine Tumors: Comparison with Somatostatin Receptor Scintigraphy and CT. Journal of Nuclear Medicine 04/2007; 48(4):508-18., DOI:10.2967/jnumed.106.035667

Clemens Decristoforo, Laura Melendez-Alafort, Jane K. Sosabowski, Stephen J. Mather: 99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor- positive tumors: Preclinical evaluation and comparison with 111In- octreotide. Journal of Nuclear Medicine 06/2000; 41(6):1114-9.
Clemens Decristoforo

Clemens Decristoforo

Department of Nuclear Medicine

Radiopharmaceuticals, Radiometal labelled peptides for diagnosis and therapy, Ga-68, radiolabelled siderophores, targeted radionuclide therapy


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E-Mail: clemens.decristoforo@i-med.ac.at